Dr. Zhang graduated with her Ph.D degree under the mentorship of Dr. Roland Kallen from the University of Pennsylvania in 1998 and joined the Cell Signaling Group with Dr. Michael Comb in New England Biolabs and moved to Cell Signal Technology as Senior Scientist. Starting in 2001, she worked in Dr. Ruedi Aebersold's proteomics group at The Institute for Systems Biology and developed glycoproteomics and label-free quantitative proteomics. In 2006, she joined Johns Hopkins University as an Assistant Professor of Pathology, was promoted to an Associate Professor in 2011, and an full professor in 2016. She established the Mass Spectrometry Core Facility of the Center for Biomarker Discovery and Translation and served as a Director from 2012. Her research focus is on developing high-throughput technologies to characterize dynamic protein and glycoprotein expressions and their modifications and using these proteomic technologies to understand human diseases. Dr. Zhang participates in several research programs and serves as an investigator in the Early Detection Research Network (EDRN), Clinical Proteomic Tumor Analysis Consortium (CPTAC), NIHBI Proteomics Center, Programs of Excellence in Glycosciences (PEG), and Pancreatic Cancer Detection Consortium (PCDC).